About the Network
Canada is at the forefront of identification of rare disease genes and this Network represents a truly national consortium that connects the infrastructure and leadership of Canada’s gene discovery projects with the model organism/system scientist communities of yeast, C.elegans (worm), zebrafish, Drosophila (‘fruit fly’), mouse, and human cell models (e.g., human pluripotent stem cells and human organoids). Network administration is provided by the Maternal Infant Child & Youth Research Network (MICYRN) which joins 28 specialist networks and 21 maternal-child health research organizations based at academic health centers across the country, ensuring engagement of clinicians and rapid communication of Network activities. The Network was initiated with funding from the CIHR Institute of Genetics and Genome Canada. Funding from Genome BC supported development of the registry of model organism scientists. The Network welcomes proposals from other organizations such as rare disease foundations who are interested in supporting catalyst grants. [contact us]
Governance Oversight Committee (GOC)The GOC is responsible for the overall coordination, accountability & administration of the Network. The GOC is chaired by the nominated principal applicant (Hieter) and includes co-applicants (Boycott and Campeau), the head of the Network Administrative-Coordinating Centre (Lacaze), and co-Chair of the Scientific Advisory Committee (Hicks).
Scientific Advisory Committee (SAC) The SAC is responsible for setting and monitoring the Network’s priorities and objectives. The SAC is responsible for inviting scientists working with model organisms to respond to clinical gene discovery proposals relevant to their areas of interest.
Co-chairs: Philip Hieter & Geoffrey Hicks
Members: Berman, Boycott, Campeau, Wozniak, Rankin, Lipshitz, Shoubridge, Nunes Vasconcelos
Clinical Advisory Committee (CAC) The CAC is responsible for setting and monitoring the clinical criteria to enable prioritization of Network projects. The CAC conducts the first review of a clinical gene discovery proposal. Submit a disease gene to establish a connection.
Co-chairs: Kym Boycott,
Members: Balci, Frosk, Dyment, Innes, Gibson
BioInformatics Core (BIC)The BIC runs a set of analyses to provide the SAC and applicant some basic information about genes of interest. The BIC also manages the Network Registry which is used to identify model organism scientists that can be invited to submit proposals to interrogate genes/pathways. Register as a Model Organism Investigator.
Chair: Paul Pavlidis
Network Administrative Coordinating CentreThe Network Coordinating Center provides logistical support to the Network committees, and is responsible for managing the receipt and flow of applications for catalyst grants, the website, and news about the Network.
Head: Thierry Lacaze